JUVGEN: Does It Work for Deep Wrinkles? Side Effects, Differences from Dermal Fillers, and Real Reviews

You may have wondered, seeing your parents' deepening nasolabial folds, "Botulinum toxin type A doesn't help—are there other options?" To be frank, deep wrinkles do not resolve with botulinum toxin type A. You might worry that dermal fillers would look unnatural, and scar lasers work slowly. That is why I recommend JUVGEN (autologous dermal regeneration) to such patients.

JUVGEN improves deep wrinkles by about 80% in a single session, and the collagen produced once is not absorbed, providing semi-permanent results. This procedure has shown the highest satisfaction, with clear before-and-after differences for my own parents as well as the parents of our hospital staff. I will explain the definite effects of JUVGEN, its differences from dermal fillers, and who it is recommended for, based on my experience.

What is JUVGEN, the procedure that even parents and relatives have received?

JUVGEN is an autologous dermal regeneration procedure that uses precise injections in 0.001 cc increments to directly induce collagen regeneration in the dermal layer, semi-permanently filling deep wrinkles. Its key feature is that the collagen produced once remains in place without being absorbed.

JUVGEN is the procedure that my own parents, elderly relatives, fellow clinic directors I have worked with, the parents of our hospital staff, and most recently the mother of the PD of the YouTube channel pibutenten that I run, have all received and been satisfied with. I have been actively recommending this procedure for quite some time. It is a short procedure lasting about 5 to 10 minutes that immediately organizes deep wrinkles, and it offers the most noticeable results relative to the time invested.

This is a bit personal, but I once performed JUVGEN on my children's tutor. After the procedure, she looked in the mirror for a long time and said, 'For a housewife, JUVGEN is it.' When I told the staff about this, they said it sounded like a tagline. I think that such a natural exclamation, without exaggeration, proves the power of JUVGEN.

A procedure that even a picky father was satisfied with—is JUVGEN really that effective?

The biggest differentiator of JUVGEN is that a single session improves deep wrinkles by about 80%, and the effect is maintained without absorption. I felt the power of JUVGEN most clearly when I performed the procedure on my own father. He usually does not like procedures and said he would not receive it because it would hurt, but before my youngest sibling's wedding, he asked me for the first time, 'Can I get more botulinum toxin type A on my forehead, glabella, and nasolabial folds?'

Knowing that deep wrinkles do not resolve with botulinum toxin type A, I recommended JUVGEN instead. A few weeks after the procedure, he said that people around him kept saying, 'Your expression has softened,' and 'You look ten years younger.' Seeing my famously picky father satisfied, I once again confirmed the power of this procedure.

There is a nuance that only a doctor who has performed the procedure can understand—how the recipient's expression changes and what small ripple that change creates within the family. JUVGEN is the procedure that most strongly brings about both of these.

Same area, different filling—what is the difference between JUVGEN and dermal fillers?

Dermal fillers are a procedure that fills hyaluronic acid in one go to shape the area, whereas JUVGEN uses precise stimulation in 0.001 cc increments to make the skin fill itself.

Many people ask why not just use dermal fillers to fill the wrinkle area. However, that is not always the case. Regular dermal fillers inject a certain amount of hyaluronic acid all at once into one spot, which can sometimes make the area look slightly raised or feel awkward when making facial expressions.

JUVGEN is different. Using an automated precision device that alternately injects into the same spot in 0.001 cc increments, it simultaneously creates physical, chemical, and biological stimulation. This stimulation directly induces collagen fiber tissue formation in the dermal layer, so immediately after the procedure it appears only subtly filled, but over 1 to 2 months, the area fills in firmly like natural tissue.

The amount of hyaluronic acid injected is less than half that of a typical dermal filler. Yet the result is actually more refined. This is because rather than "filling in" the same amount all at once, it uses a small amount to allow the skin to "fill itself in." This principle was published as a cover article in the SCI-level international journal Annals of Plastic Surgery and has been academically validated.

Beyond nasolabial folds, glabellar lines, and forehead wrinkles, is JUVGEN effective for scars as well?

JUVGEN is a procedure that can be applied to a wide range of concerns, including nasolabial folds, glabellar lines, and forehead wrinkles, as well as deep crow's feet that do not resolve with botulinum toxin type A, the area around the mouth, marionette lines, and even acne scars and chickenpox marks.

The uses of JUVGEN are not limited to one area. It is being used in various fields ranging from cosmetic to therapeutic applications.

📌 Nasolabial folds: The area with the highest satisfaction; deep, sunken lines are naturally filled.

📌 Glabellar lines and forehead wrinkles: Effective for static wrinkles that do not improve with botulinum toxin type A.

📌 Crow's feet: Applied to fine lines that have become so deep that botulinum toxin type A can no longer smooth them out.

📌 Area around the mouth and marionette lines: Neatly refines deep lines that have formed below the corners of the mouth.

📌 Acne scars and chickenpox marks: One JUVGEN session can produce the same change as 2 to 3 sessions of scar laser treatment.

The change in the area of scars is particularly noticeable. For areas that have been sunken for a long time, one JUVGEN session can produce the same change as 2 to 3 sessions of scar laser treatment. There is data showing that approximately 80% improvement is achieved in deep wrinkles after a single treatment, meaning the scope of change from one procedure is significant. This is very welcome news for those who have given up and live with scars.

Are there any side effects with JUVGEN? What about downtime?

Side effects are mild. The treated area may appear slightly red for 1 to 2 weeks, and you may notice a very subtle bumpy texture, but as collagen settles in, it naturally becomes smoother. Mild side effects include

The treated area may become red. It may appear slightly red for 1 to 2 weeks. You may feel a bumpy texture initially. The micro-filled area may feel slightly bumpy at first, but as new collagen settles, it will naturally become smoother over time. There may be mild swelling immediately after the procedure, but it usually subsides within 2 to 3 days.

If I get JUVGEN, do I still need botulinum toxin type A?

We receive this question very often in the clinic. "Now that I've had JUVGEN, I don't need to get botulinum toxin type A injections anymore, right?" The answer is "no." No. JUVGEN and botulinum toxin type A are procedures with completely different roles, so it is advisable to use them together.

JUVGEN is a procedure that fills already sunken folds, while botulinum toxin type A prevents new folds from forming. Because their roles are different, the most effective combination is to fill sunken areas with JUVGEN and prevent new wrinkles from deepening with botulinum toxin type A. It is advisable to view them as complementary rather than competitive.

Will JUVGEN work well for me? Who is JUVGEN most effective for?

It seems most suitable for those who are bothered by deep wrinkles that do not resolve with botulinum toxin type A, and for those who wish to give a gift of care to their parents.

📌 Those who have deep nasolabial folds, glabellar lines, or forehead wrinkles that do not improve with botulinum toxin type A. Static wrinkles etched by time do not resolve with botulinum toxin type A. JUVGEN is most appropriate.

📌 Those who wish to give a gift of care to their parents. When you think, "They look so much older...", a single procedure can restore their original expression.

📌 Those who have long been troubled by acne scars or chickenpox marks. You can expect the same change from one session as from 2 to 3 sessions of scar laser treatment.

📌 Those who have had an experience with dermal filler that felt unnatural. Precision injection in 0.001 cc increments allows it to fill in as naturally as real tissue.

📌 Those who want semi-permanent results. Because the collagen is not absorbed, once it settles, the area remains almost unchanged.

Conversely, for those who only have superficial expression wrinkles, botulinum toxin type A alone is often sufficient rather than JUVGEN, so we help you choose the most appropriate procedure through consultation.

The procedure called a gift of care. Why I call JUVGEN a gift of care

For those who see the deepened wrinkles on their parents' faces and feel how much they have aged without them realizing it, JUVGEN may be a procedure that can lightly ease that burden. That is why I would like to call JUVGEN the leading "gift of care" procedure. It does not create anything new, but quietly fills the deep marks etched by time, restoring the original expression on a parent's face. As a doctor who has actually performed it on my own family, that feeling was truly heartwarming.

If you are considering recommending JUVGEN to your parents, feel confident in proceeding. At Heal House Gangnam Branch, board-certified dermatologist Dr. Hanmi Jung is with you from the initial consultation through the procedure and aftercare, from start to finish.

[Quick Q&A]

Q. How long does the JUVGEN procedure take? It varies by area but takes approximately 20 to 40 minutes. Even including your total time at the clinic, it is completed within 1 hour.

Q. When do the effects of JUVGEN become noticeable? Immediately after the procedure, it may appear to be only minimally filled, but over 1 to 2 months, as collagen settles, the real change becomes apparent. Deep wrinkles improve by approximately 80% after a single session.

Q. How long do the effects of JUVGEN last? The most distinctive feature of JUVGEN is that the collagen created once is not absorbed and remains in place, providing semi-permanent results.

Q. Which is better, JUVGEN or regular dermal filler? Their purposes are different. For areas that need shape (forehead, nose, chin), dermal filler is suitable. For naturally filling deep wrinkles (nasolabial folds, glabellar lines, crow's feet), JUVGEN is appropriate.

Q. Can I receive JUVGEN and botulinum toxin type A together? Yes, receiving them together is most effective. This is because JUVGEN fills already sunken wrinkles, while botulinum toxin type A prevents new wrinkles from forming.

Q. Is JUVGEN effective for scars as well? Yes. It can be applied to long-standing scars such as acne scars and chickenpox marks, and one session produces the same change as 2 to 3 sessions of scar laser treatment.

Q. How much does JUVGEN cost? The cost varies depending on the treatment area and scope, so the exact price will be provided during a 1:1 consultation.

Q. Can I return to daily life right after JUVGEN treatment? The treated area may appear slightly red for about 1 to 2 weeks, but it does not significantly interfere with daily activities.

[Tags] #JUVGEN #Juvegen #autologous dermal regeneration #deep wrinkle treatment #depressed scar #semi-permanent wrinkle #filial piety treatment #parent treatment #Heal House Gangnam #nasolabial fold treatment #deep wrinkle treatment