PN (polynucleotide) is a regenerative substance extracted from salmon DNA that is very similar to human DNA, so it has low foreign body reaction. Unlike ordinary moisturizing boosters that simply fill the skin with moisture and stop, it directly stimulates fibroblasts in the dermis layer, changing the internal environment of the skin to be healthy so that it produces collagen and elastic fibers on its own. In other words, the PN component forms a strong mesh (framework) inside the skin, creating an optimal environment for damaged cells to recover well, and plays a key role in rebuilding the collapsed skin structure firmly from within.
What role does the PN ingredient play?
How does it help with regeneration and anti-inflammation?
The PN component has excellent anti-inflammatory effects that help recovery of damaged tissue and soothe irritated skin. Therefore, it is very effective for calming and regenerating skin in people whose skin barrier has become thin, red, and sensitive due to frequent laser treatments or external irritation, or for skin that is slow to recover after inflammation. (However, it is not a medication that directly treats skin diseases themselves, so if you have ongoing severe inflammation, it is safer to first determine the order of treatment and procedure through a consultation.)
What skin concerns is REJURAN® suitable for?
Unlike dermal fillers that fill volume in specific areas, this procedure improves the overall 'basic stamina' of the skin, so it is actively recommended for people whose skin has become thin, dry, and aging. In particular, it can be safely applied to areas where the skin is thin and other procedures are burdensome, such as the neck or eye area.
- Fine lines and texture improvement: Reduces fine lines on thin skin such as around the eyes and mouth through dermal regeneration.
- Dryness and tightness: Resolves roughness by improving the hydration environment of the dermis layer.
- Redness and sensitivity: Restores the collapsed skin barrier and soothes redness.
When will I see results from REJURAN®?
About 1 to 2 weeks after the procedure, the moisture-oil balance is adjusted, and you first notice smoother skin texture and improved hydration. Then, as collagen regeneration begins in earnest, effects on elasticity and fine lines follow. Because it is a method that helps the skin recover on its own rather than producing immediate changes with artificial substances, the improvement gradually accumulates with each session rather than being immediate like dermal fillers. You may continue to feel your skin condition improve over several months after the last session.
How many sessions of REJURAN® are recommended?
To feel the cumulative effect of collagen regeneration sufficiently, it is much more important to complete a certain number of sessions rather than a single session. The most recommended protocol is typically 3 intensive sessions at 4-week intervals to fully improve the skin environment, followed by maintenance sessions every 3 to 6 months. Of course, skin that has aged significantly or has a high degree of damage may require more sessions, while for younger people for preventive purposes, fewer sessions may be sufficient.
We recommend that you have a consultation to check your skin condition and then establish a plan tailored to you, including the number of sessions and intervals.
