Generally, an initial intensive course of about 3 sessions at 2- to 4-week intervals is the standard protocol. This is because a collagen booster does not create volume through the injected substance itself; instead, it stimulates fibroblasts in the skin to produce collagen on their own. Time is needed for newly synthesized collagen to settle, and repeating the process several times makes the improvement more noticeable.
However, the interval and number of sessions vary depending on the product ingredients, skin thickness, degree of aging, and the desired level of improvement. For example, Sculptra, which contains PLLA, is often administered at intervals of 4 weeks or more, with the number of sessions determined by the volume needed. REJURAN®, which contains PN (polynucleotide), is often based on 3 sessions at 1-month intervals. It is safer to determine the exact number of sessions after assessing your skin condition.



