PICOPLUS emits laser pulses as short as 450 picoseconds. The shorter the irradiation time, the more the energy is concentrated on the pigment particles without spreading as heat, allowing pigment to be finely fragmented while reducing thermal damage to surrounding tissue. The fragmented pigment is processed by immune cells and eliminated from the body. Each wavelength is absorbed by different colors: 1064 nm targets deep pigment, 532 nm targets brown pigment in the epidermis, and the 595 nm and 660 nm handpieces are used for colors that were difficult to treat with existing wavelengths.