Is HP VITARAN the same as what is commonly called 'Rejuran'?

Because it uses DNA ingredients derived from salmonid fish, it is often collectively referred to as Rejuran. HP VITARAN is an injection containing purified polynucleotide (PN) among these, and is a Skin Booster focused on improving the skin's regenerative environment and soothing, rather than adding volume.

Does HP VITARAN hurt a lot during the procedure? Is anesthesia used?

Since HP VITARAN is injected into the dermis in multiple divided doses, some stinging may occur. Therefore, when receiving it by manual injection, applying anesthetic cream is essential. However, when using the Dermashine PRO injection device, the procedure can be performed with no downtime and no pain, so anesthetic cream may be skipped and the procedure done directly.

Do swelling or bruises occur a lot after HP VITARAN treatment? Can I resume activities right away?

After HP VITARAN treatment, redness, mild swelling, and faint bruising may appear at the injection sites, and these usually subside within 1 to 3 days. In areas with thin skin or sensitive areas like the eye area, they may last a little longer, so soothe them with a cold compress and avoid vigorous massage.

When will I feel the effects of HP VITARAN, and how long do they last?

Many people feel a sense of hydration and brightness from the first session of HP VITARAN, and changes in elasticity tend to become more noticeable as sessions accumulate. After completing about 3 sessions, the effects last for several months, but the duration may vary depending on your skin condition and subsequent care habits.

How many sessions of HP VITARAN should I receive, and at what intervals?

HP VITARAN is typically performed in about 3 sessions at 3 to 4 week intervals to build a foundation for skin condition, and then maintenance is done with wider intervals. The number of sessions and intervals may vary depending on your skin condition and desired goals, so they will be determined after a consultation.

Are there cases where HP VITARAN is difficult to receive?

HP VITARAN is not recommended for those who are pregnant or breastfeeding, or who have had hypersensitivity reactions to fish-derived ingredients. A consultation is also needed first if you have a keloid tendency, an autoimmune disease, a bleeding tendency such as from taking anticoagulants, or if there is inflammation at the treatment site.

Comfortable skin regeneration without pain HP VITARAN

A delicate skin booster that delivers a component approved for improving fine lines around the eyes into the dermis, helping regeneration even in thin, sensitive areas.

Treatment Time: About 30–40 minutes including anesthesia
Anesthesia: Performed after topical anesthesia
Recovery Time: Swelling and bruising for 1–3 days
Recommended Interval: 3 sessions at 3–4 week intervals, then maintenance

Anti-Aging Skin Booster

vitaran

What is HP VITARAN?

HP VITARAN is a Skin Booster injection containing polynucleotide (PN) purified from the reproductive cells of salmonid fish. It improves the regenerative environment of the dermis and helps soothe the skin, and is used to manage loss of elasticity, dryness, and rough skin texture.

01 Vitality
02 Inner dryness
03 Skin tone

Mechanism

How HP VITARAN works

HP VITARAN is a Skin Booster that injects polynucleotide (PN) purified from the reproductive cells of salmonid fish into the dermis. PN, which has a structure similar to human DNA, improves the skin's regenerative environment and helps soothe irritated skin. At the same time, it enhances the skin's ability to retain moisture, alleviating inner dryness. With repeated treatments, skin texture becomes smoother, and elasticity and brightness improve together.

Damaged and aged skin
Strengthened skin structure after HP VITARAN treatment

Effects

Effects of HP VITARAN

Skin soothing through improved regenerative environment
Alleviation of inner dryness through improved moisture retention
Improvement of fine lines around the eyes and mouth and skin texture

Device Specifications

Manufacturer: Manufacturer: BR PHARM Co., Ltd. (CEO Kim Seok-soon) / Domestic introduction and distribution: LG Chem
Official Product Name: HP Cell VITARAN / HP VITARAN PN SKINBOOSTER (Lineup: HP VITARAN, VITARAN Eye (i), etc.)
Main component/Principle: Polynucleotide sodium — derived from rainbow trout (Oncorhynchus mykiss) testicular DNA
Treatment depth/Layer: Dermis
Specifications/Capacity: 2 units/box, expiration date 3 years from manufacture date

Who It's For

Have sensitive skin with lingering redness due to frequent treatments and irritation
Experience severe inner dryness, with skin that constantly feels tight and rough in texture
Are starting to notice fine lines around the eyes and mouth
Want to calmly enhance the skin's natural regenerative ability

Adverse Effects

Side Effects and Adverse Reactions

After HP VITARAN treatment, redness, mild swelling, and faint bruising may appear at the injection sites, which usually subside within 1–3 days. These may last a little longer in thin or sensitive areas such as the eye area.

Common Symptoms

Redness, mild swelling, faint bruising

Rare Symptoms

Small bumps (embossing), hypersensitivity reaction to fish-derived ingredients

If Symptoms Persist

If adverse reactions persist or worsen, please contact the clinic where you received the treatment.
Other rare adverse reactions and individual risk factors will be explained in detail during your pre-treatment consultation.

FAQ

HP VITARAN, frequently asked questions

HP VITARAN is a treatment that involves multiple injections into the dermis, so some stinging sensation may occur. Therefore, when receiving it by manual injection, applying anesthetic cream is essential. However, when using an injection device called Dermashine PRO, the treatment can be performed without downtime and painlessly, so the anesthetic cream may be omitted and the procedure done directly.

Aftercare

Post-Treatment Care

Gently wash your face and apply makeup about three to four hours after the procedure.
Use a cold compress to reduce redness and swelling at the injection sites.
Avoid activities that sharply increase blood flow, such as drinking alcohol and using saunas, for 2 to 3 days.
Apply sunscreen thoroughly and replenish moisture with a moisturizer.

COMPARISON

What is the difference between REJURAN® and HP VITARAN?

Main Ingredient Polynucleotide Sodium 20 mg/mL Polynucleotide Sodium

Source Salmon DNA Rainbow Trout Testis DNA

Target Layer Superficial Dermis Dermis

Specification — 2 units/box, expiration 3 years from manufacture date

Recovery Bumps & Bruising 2–7 days Swelling & Bruising 1–3 days

Recommended Interval 3 sessions at 3–4 week intervals, then maintenance 3 sessions at 3–4 week intervals, then maintenance

Synergy

Treatments that go well with HP VITARAN

HEALHOUSE’S vitaran

Heal House's HP VITARAN is different

HEAL POINT 01

Genuine products Accurate shots Exact dosage

All five Heal House branches use only genuine products, under the same standards. This applies to tips, cartridges, and medications alike. We use the agreed number of shots and dosage as planned, and disposable supplies are never reused. We deliver the exact amount precisely where it is needed.

HEAL POINT 02

Same procedure, different design

Even with the same equipment and medication, results vary depending on who receives the treatment and how it is applied
. This is because skin type, thickness, and degree of sagging differ from person to person. A higher number of shots or larger dosage does not necessarily mean better results.
A different design leads to different outcomes.

A specialist examines the patient's skin condition and designs a customized treatment

HEAL POINT 03

We read your skin first

We recommend only what your skin truly needs at this moment.

3D Skin Analysis

We analyze your current skin condition, including elasticity, sagging, and texture.
Specialist Consultation

A dermatologist directly examines your skin and plans the treatment direction.
Customized Design

We determine the necessary treatments, areas, and dosages.
Pain Management

We prepare measures to reduce discomfort before the procedure.
Performed by a Specialist

The procedure is performed precisely while monitoring your skin's response.
Follow-up Appointment

We consistently manage changes in your skin.

HEAL POINT 04

Both consultation and treatment are performed by board-certified dermatologists

Only 2% of doctors in South Korea are board-certified dermatologists. All procedures at Heal House are performed by a dermatologist with over 1,000 cases of experience. The design, the procedure, and the responsibility all lie with the specialist you meet in the consultation room.

HEALHOUSE’S HP VITARAN

Heal House
HP VITARAN treatment branches

Heal House's Promise

While everyone chases the same standard of beauty,
Heal House studies your most radiant, authentic moments.

Design tailored to your facial structure

We consider the balance of your facial features and bone structure to find
the most natural line that suits your face.
Treatments we would recommend to our own family

A dermatologist with over 10 years of experience prioritizes the safest methods and performs each procedure with care.
Beauty that is most true to you

Rather than artificial change, we help you get closer to the moment when your skin was at its most radiant.

References

Columns

From equipment to post-treatment care,
columns written directly by our dermatologists

SKIN BOOSTER

Comfortable skin regeneration without pain HP VITARAN

What is HP VITARAN?

How HP VITARAN works